Aims
Discovery of metabolic biomarkers and innovative therapeutic strategies aimed at improving age-related diseases due to altered metabolism.
Underlying Mechanisms
Immunology
Aims
Elucidate the role of immune cells and of their products in age-related pathologies; Develop and test new immunotherapeutic strategies; Elucidate the impact of ageing on immune cell function
Leader name(s)
Pr N. Glaichenhaus
Pr B. Seitz-Polski
Genome stability
Aims
The WP « Genome Stability » of ONCOAGE has built an interdisciplinary proposal that will:
(1) investigate how DNA and chromatin alterations drive ageing and age-related pathologies;
(2) develop innovative genomic biomarkers and assays to evaluate frailty in elderly patients, to model age-related pathologies, including cancer, and to screen anti-ageing as well as anti-cancer drugs.