Metabolism

Aims

Discovery of metabolic biomarkers and innovative therapeutic strategies aimed at improving age-related diseases due to altered metabolism.

Leader name(s)

Pr L. Yvan-Charvet
Pr E. Van Obberghen

Immunology

Aims

Elucidate the role of immune cells and of their products in age-related pathologies; Develop and test new immunotherapeutic strategies; Elucidate the impact of ageing on immune cell function

Leader name(s)

Pr N. Glaichenhaus
Pr B. Seitz-Polski

Genome stability

Aims

The WP « Genome Stability » of ONCOAGE has built an interdisciplinary proposal that will:

(1) investigate how DNA and chromatin alterations drive ageing and age-related pathologies;

(2) develop innovative genomic biomarkers and assays to evaluate frailty in elderly patients, to model age-related pathologies, including cancer,  and to screen anti-ageing as well as anti-cancer drugs.

Leader name(s)

Pr E. Gilson
Pr C. Falandry